Presstek Reports Improved Sequential First Quarter 2011 Revenue and Profit

• 52DI and open architecture computer-to-plate media sales up 23% and 31%, respectively

HUDSON, NH—May 9, 2011—Presstek, Inc. (NASDAQ: PRST), a leading supplier of digital offset printing solutions to the printing and communications industries, today reported financial and operating results for the first quarter ended April 2, 2011. In the quarter, the Company reported total revenue of $31.9 million, a decline of 7.6% from the amount reported in the first quarter of 2010, and an increase of 2.6% from the fourth quarter of 2010.